Current Concepts of Cerebrovascular Disease — Stroke Neurological Manifestations of Systemic Lupus Erythematosus and Thrombotic Thrombocytopenic Purpura

NEUROPSYCHIATRIC SYMPTOMS and signs are a prominent part of systemic lupus erythematosus (SLE) and thrombotic thrombocytopenic purpura (TTP). These disorders are similar also in that they frequently share such clinical manifestations as hemolytic anemia, thrombocytopenia, renal disease, and fever. Adding to the complexity of diagnosis is the fact that patients may occasionally have clinical and laboratory evidence of both disorders. This article will review these disorders with emphasis on neurological manifestations.